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<script type="application/ld+json">{"@context":"https://schema.org","@type": "WebPage","@id":"#main","mainEntityOfPage":{"@type":"WebPage", "@id":"http://e-cep.org"}, "headline":"","description":"ARTICLE CATEGORYÂ","about":[{"@type": "Thing","name": "Clinical","sameAs": ["https://en.wikipedia.org/wiki/Medicine", "https://www.wikidata.org/wiki/Q11190"]},{"@type": "Thing","name": "Research","sameAs": ["https://en.wikipedia.org/wiki/Research", "https://www.wikidata.org/wiki/Q42240"]},{"@type": "Thing","name": "publication","sameAs": ["https://en.wikipedia.org/wiki/Publication"]},{"@type": "Person","name": "Jiyeon Oh"},{"@type": "Person","name": "Michael Miligkos"},{"@type": "Thing","name": "Pediatric","sameAs": ["https://en.wikipedia.org/wiki/Pediatrics", "https://www.wikidata.org/wiki/Q123028"]}],"author":{"@type":"Organization","url":"/","name":"/"},"publisher":{"@type":"Organization", "name":"/", "url":"/", "logo": {"@type": "ImageObject", "url": "http://www.example.com", "width": 4, "height": 97}},"datePublished":"2025-05-11T02:52:37","dateModified":"2025-05-11T02:52:37"}</script>
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Clinical<span itemscope itemtype="http://schema.org/Thing">
<span itemprop="name">Clinical</span>
<link itemprop="sameAs" href="https://en.wikipedia.org/wiki/Medicine" />
</span> and Experimental Pediatrics
Article 68(5); May 2025
Tae Hyeon Kim, Hyunjee Kim, Jiyeon Oh<span itemscope itemtype="http://schema.org/Person">
<span itemprop="name">Jiyeon Oh</span>
</span>, Soeun Kim, Michael Miligkos<span itemscope itemtype="http://schema.org/Person">
<span itemprop="name">Michael Miligkos</span>
</span>, Dong Keon Yon<span itemscope itemtype="http://schema.org/Person">
<span itemprop="name">Dong Keon Yon</span>
</span>, NikolaoChronics<span itemscope itemtype="http://schema.org/Thing">
<span itemprop="name">Chronics</span>
<link itemprop="sameAs" href="https://en.wikipedia.org/wiki/Chronic_condition" />
</span> G Papadopoulos
Clin Exp Pediatr. 2025;68(5):329-343. Â Â Published online April 22 , 2025
Pediatric<span itemscope itemtype="http://schema.org/Thing">
<span itemprop="name">Pediatric</span>
<link itemprop="sameAs" href="https://en.wikipedia.org/wiki/Pediatrics" />
</span> asthma<span itemscope itemtype="http://schema.org/MedicalCondition">
<span itemprop="name">asthma</span>
<link itemprop="sameAs" href="https://en.wikipedia.org/wiki/Asthma" />
</span> can persist to adulthood and must be effectively managed.
9 years. Despite a projected continued decrease in prevalence by 2050, asthma will remain a significant health<span itemscope itemtype="http://schema.org/Thing">
<span itemprop="name">health</span>
<link itemprop="sameAs" href="https://en.wikipedia.org/wiki/Health" />
</span> concern for children<span itemscope itemtype="http://schema.org/Thing">
<span itemprop="name">children</span>
<link itemprop="sameAs" href="https://en.wikipedia.org/wiki/Child" />
</span> and adolescents<span itemscope itemtype="http://schema.org/Thing">
<span itemprop="name">adolescents</span>
<link itemprop="sameAs" href="https://en.wikipedia.org/wiki/Adolescence" />
</span>.
Anjali Kumar, Pramodh Vallabhaneni
Clin Exp Pediatr. 2025;68(5):344-351. Â Â Published online January 13 , 2025
A positive bidirectional relationship between gastrointestinal<span itemscope itemtype="http://schema.org/Thing">
<span itemprop="name">gastrointestinal</span>
<link itemprop="sameAs" href="https://en.wikipedia.org/wiki/Gastrointestinal_tract" />
</span> disorders and anxiety<span itemscope itemtype="http://schema.org/MedicalCondition">
<span itemprop="name">anxiety</span>
<link itemprop="sameAs" href="https://en.wikipedia.org/wiki/Anxiety" />
</span>, but with no clear aetiology, was identified. Factors such as somatisation and pain<span itemscope itemtype="http://schema.org/MedicalCondition">
<span itemprop="name">pain</span>
<link itemprop="sameAs" href="https://en.wikipedia.org/wiki/Pain" />
</span> catastrophising resulted in poorer pain-related outcomes in children. Further studies are required to understand this relationship in order to have targeted treatments<span itemscope itemtype="http://schema.org/Thing">
<span itemprop="name">treatments</span>
<link itemprop="sameAs" href="https://en.wikipedia.org/wiki/Therapy" />
</span> and ensure better long term outcomes.
Jong Woo Hahn<span itemscope itemtype="http://schema.org/Person">
<span itemprop="name">Jong Woo Hahn</span>
</span>, MinSoo Shin, Jin Gyu Lim<span itemscope itemtype="http://schema.org/Person">
<span itemprop="name">Jin Gyu Lim</span>
</span>, Yoon-Joo Kim<span itemscope itemtype="http://schema.org/Person">
<span itemprop="name">Yoon-Joo Kim</span>
</span>, Ki Soo Kang, Narae Lee, Seong Hee Jeong, Mun Hui Jeong, Yeoun Joo Lee, Eui Kyung Choi, Jung Ok Shim<span itemscope itemtype="http://schema.org/Person">
<span itemprop="name">Jung Ok Shim</span>
</span>, Jee Yoon Park<span itemscope itemtype="http://schema.org/Person">
<span itemprop="name">Yoon Park</span>
</span>, Chan-Wook Park, Joo Young Kim, Su Jin Jeong, Young Hwa Jung, Jaehyun Kim, Chang Won Choi<span itemscope itemtype="http://schema.org/Person">
<span itemprop="name">Chang Won Choi</span>
</span>, Ju Whi Kim, Seung Han Shin, Yun Jeong Lee, Young Ah Lee, Choong-Ho Shin, Seung-sik Hwang, Young Eun Kim, Youn Ha Kang<span itemscope itemtype="http://schema.org/Person">
<span itemprop="name">Ha Kang</span>
</span>, Kyungwon Oh, Sungha Yun, Jae Sung Ko<span itemscope itemtype="http://schema.org/Person">
<span itemprop="name">Sung Ko</span>
</span>, Jin Soo Moon<span itemscope itemtype="http://schema.org/Person">
<span itemprop="name">Jin Soo Moon</span>
</span>
Clin Exp Pediatr. 2025;68(5):352-358. Â Â Published online February 13 , 2025
The suitability of World Health Organization<span itemscope itemtype="http://schema.org/Organization">
<span itemprop="name">World Health Organization</span>
<link itemprop="sameAs" href="https://en.wikipedia.org/wiki/World_Health_Organization" />
</span> (WHO) growth charts<span itemscope itemtype="http://schema.org/Thing">
<span itemprop="name">charts</span>
<link itemprop="sameAs" href="https://en.wikipedia.org/wiki/Chart" />
</span> for assessing the growth of children under 3 years of age in all countries remains controversial, and their applicability must be evaluated based on country-specific growth data. The Korea Infant Physical Growth Examination Survey evaluated the suitability of WHO growth charts to contribute to the next revision of growth charts in Korea.
Jongin Lee, Dong-Wook Lee<span itemscope itemtype="http://schema.org/Person">
<span itemprop="name">Dong-Wook Lee</span>
</span>
Clin Exp Pediatr. 2025;68(5):359-361. Â Â Published online November 13 , 2024
The ecological impacts of microplastics<span itemscope itemtype="http://schema.org/Thing">
<span itemprop="name">microplastics</span>
<link itemprop="sameAs" href="https://en.wikipedia.org/wiki/Microplastics" />
</span> have been documented. It was recently recognized that they can directly or indirectly cause diseases<span itemscope itemtype="http://schema.org/Thing">
<span itemprop="name">diseases</span>
<link itemprop="sameAs" href="https://en.wikipedia.org/wiki/Disease" />
</span> in humans.
There are few established methods for assessing human exposure to microplastics.
Standardization of exposure assessments and large-scale epidemiological<span itemscope itemtype="http://schema.org/Thing">
<span itemprop="name">epidemiological</span>
<link itemprop="sameAs" href="https://en.wikipedia.org/wiki/Epidemiology" />
</span> studies are required to explore the human effects of microplastics.
Soyoung Lee, Kyung-Hyo Kim, Ji Hyen Lee, Han Wool Kim
Clin Exp Pediatr. 2025;68(5):362-369. Â Â Published online January 13 , 2025
Question: What is the level of immunity<span itemscope itemtype="http://schema.org/Thing">
<span itemprop="name">immunity</span>
<link itemprop="sameAs" href="https://en.wikipedia.org/wiki/Immunity_(medical)" />
</span> against meningococcal infections in patients<span itemscope itemtype="http://schema.org/Thing">
<span itemprop="name">patients</span>
<link itemprop="sameAs" href="https://en.wikipedia.org/wiki/Patient" />
</span> with systemic lupus erythematosus<span itemscope itemtype="http://schema.org/Thing">
<span itemprop="name">systemic lupus erythematosus</span>
<link itemprop="sameAs" href="https://en.wikipedia.org/wiki/Systemic_lupus_erythematosus" />
</span> (SLE) under the age of 19, and is vaccination against meningococcus necessary for these patients, given their susceptibility to infections due to immunosuppressive treatments and disease characteristics?
Finding: Although some of our study patients exhibited serum bactericidal<span itemscope itemtype="http://schema.org/Thing">
<span itemprop="name">bactericidal</span>
<link itemprop="sameAs" href="https://en.wikipedia.org/wiki/Bactericide" />
</span> activity against meningococci, most remained seronegative.
Meaning: These findings suggest that patients with SLE who are at risk of meningococcal infection receive appropriate vaccinations.
Anekchoke Tangtongsoong, Chonnikant Visuthranukul, Yuda Chongpison, Sirinuch Chomtho
Clin Exp Pediatr. 2025;68(5):370-378. Â Â Published online February 3, 2025
Question: How do dietary intake and physical activity affect body mass index<span itemscope itemtype="http://schema.org/Thing">
<span itemprop="name">body mass index</span>
<link itemprop="sameAs" href="https://en.wikipedia.org/wiki/Body_mass_index" />
</span> (BMI) z scores and adiposity among children with obesity<span itemscope itemtype="http://schema.org/MedicalCondition">
<span itemprop="name">obesity</span>
<link itemprop="sameAs" href="https://en.wikipedia.org/wiki/Obesity" />
</span>?
Finding: Higher dietary protein<span itemscope itemtype="http://schema.org/Thing">
<span itemprop="name">protein</span>
<link itemprop="sameAs" href="https://en.wikipedia.org/wiki/Protein_(nutrient)" />
</span> and fiber<span itemscope itemtype="http://schema.org/Thing">
<span itemprop="name">fiber</span>
<link itemprop="sameAs" href="https://en.wikipedia.org/wiki/Fiber" />
</span> intakes were significantly associated with a decrease in BMI z scores and adiposity among children with obesity.
Meaning: Optimizing dietary interventions by focusing on protein and fiber intakes could be an effective strategy for managing childhood<span itemscope itemtype="http://schema.org/Thing">
<span itemprop="name">childhood</span>
<link itemprop="sameAs" href="https://en.wikipedia.org/wiki/Childhood" />
</span> obesity.
Aseel Mahmood Ibrahim<span itemscope itemtype="http://schema.org/Person">
<span itemprop="name">Mahmood Ibrahim</span>
</span> Al-Mashahedah, Randa Mohammed Dhahi<span itemscope itemtype="http://schema.org/Person">
<span itemprop="name">Mohammed Dhahi</span>
</span>
Clin Exp Pediatr. 2025;68(5):379-387. Â Â Published online December 23 , 2024
Question: What are the most common enteric<span itemscope itemtype="http://schema.org/Thing">
<span itemprop="name">enteric</span>
<link itemprop="sameAs" href="https://en.wikipedia.org/wiki/Human_gastrointestinal_tract" />
</span> pathogens in acute<span itemscope itemtype="http://schema.org/Thing">
<span itemprop="name">acute</span>
<link itemprop="sameAs" href="https://en.wikipedia.org/wiki/Acute_(medicine)" />
</span> diarrhea<span itemscope itemtype="http://schema.org/MedicalCondition">
<span itemprop="name">diarrhea</span>
<link itemprop="sameAs" href="https://en.wikipedia.org/wiki/Diarrhea" />
</span> among children younger than 5 years of age, and which age group is most susceptible?
Finding: Bacteria<span itemscope itemtype="http://schema.org/Thing">
<span itemprop="name">Bacteria</span>
<link itemprop="sameAs" href="https://en.wikipedia.org/wiki/Gut_flora" />
</span> were the most common causative microorganisms<span itemscope itemtype="http://schema.org/MedicalCondition">
<span itemprop="name">microorganisms</span>
<link itemprop="sameAs" href="https://en.wikipedia.org/wiki/Microorganism" />
</span> of diarrhea, followed by viruses<span itemscope itemtype="http://schema.org/MedicalCondition">
<span itemprop="name">viruses</span>
<link itemprop="sameAs" href="https://en.wikipedia.org/wiki/Virus" />
</span>, parasites, and fungi.
2-year age group was the most commonly affected.
Meaning: There is a need to formulate preventive strategies<span itemscope itemtype="http://schema.org/Thing">
<span itemprop="name">strategies</span>
<link itemprop="sameAs" href="https://en.wikipedia.org/wiki/Strategy" />
</span> targeting children exposed to enteric pathogens to limit diarrhea.
Clin Exp Pediatr. 2025;68(5):388-394. Â Â Published online January 13 , 2025
Zinc<span itemscope itemtype="http://schema.org/Organization">
<span itemprop="name">Zinc</span>
<link itemprop="sameAs" href="https://en.wikipedia.org/wiki/Zinc_(band)" />
</span> may play a key role in preventing febrile seizures<span itemscope itemtype="http://schema.org/Thing">
<span itemprop="name">febrile seizures</span>
<link itemprop="sameAs" href="https://en.wikipedia.org/wiki/Febrile_seizure" />
</span> by increasing the seizure threshold and reducing oxidative stress<span itemscope itemtype="http://schema.org/Thing">
<span itemprop="name">stress</span>
<link itemprop="sameAs" href="https://en.wikipedia.org/wiki/Stress_(biology)" />
</span>. Incorporating zinc supplements into treatment could help protect children from the adverse effects of febrile seizures and improve their overall outcomes.
Upasana Ghosh, Ankit Agrawal, Umesh Shukla, Vikas Jain<span itemscope itemtype="http://schema.org/Person">
<span itemprop="name">Vikas Jain</span>
</span>, Deeksha Bhalla
Clin Exp Pediatr. 2025;68(5):395-397. Â Â Published online March 11 , 2025
Chronic abdominal pain caused by a gastric<span itemscope itemtype="http://schema.org/Thing">
<span itemprop="name">gastric</span>
<link itemprop="sameAs" href="https://en.wikipedia.org/wiki/Stomach" />
</span> trichobezoar is extremely rare among children.
An indentable epigastric mass is characteristic and upper gastrointestinal endoscopy is diagnostic of a gastric trichobezoar.
Symptomatic<span itemscope itemtype="http://schema.org/Thing">
<span itemprop="name">Symptomatic</span>
<link itemprop="sameAs" href="https://en.wikipedia.org/wiki/Symptomatic_treatment" />
</span> large trichobezoars usually require surgery.
Neuropsychiatric disorders are often associated with gastric trichobezoar, making a psychiatric evaluation of paramount importance.
Neurodevelopmental outcomes of preterm infants
Association of gut microbiota with obesity in children and adolescents
Nonalcoholic fatty liver disease and insulin resistance in children
Intermittent sigh breaths during high-frequency oscillatory ventilation among newborn infants
Cost-effectiveness of newborn screening for severe combined immunodeficiency: a systematic review